My 1989 mercedes 300e alarm is going off, and I am unable to lock are crank it up HELP!

Is it a factory alarm ? (I don't know whether or not the '89 W124 had that)
but the first thing to do is open the door, release the hood latch, open the hood and take out the appropriate fuse, (your owner's manual should point to which one that is)

I think the fuse box is in front of the firewall, left side(?) but not sure...

If it is one of those aftermarket car alarms, that's another matter, most of them are well made but when the installers are done with them, it was like they got put in by monkeys at midnight

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