The seals are shot. The hole is for pressure relief between the inner and outer seal. The only real risk is the plug of silicone popping out, which I imagine it will do in fairly short order, so the only risk is losing the coolant, which you're used to already anyways.
Yes the rear ones are hard, but not impossible. Just need a medium sized extension and a swivel adapter and a "can do" attitude. I don't let tits1 intimidate me, why let 2 lousy bolts intimidate YOU?
Gilly
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